GCM2 anticorps (Center)
Aperçu rapide pour GCM2 anticorps (Center) (ABIN2856796)
Antigène
Voir toutes GCM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Attributs du produit
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Rabbit polyclonal antibody to GCM2 (glial cells missing homolog 2 (Drosophila))
GCM2 antibody [N3C3] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human GCM2. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
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Commentaires
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Positive Control: A431
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.75 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- GCM2 (Glial Cells Missing Homolog 2 (GCM2))
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Autre désignation
- GCM2
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Sujet
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This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism.
Cellular Localization: Nucleus -
Poids moléculaire
- 57 kDa
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ID gène
- 9247
Antigène
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