ALDH1A1 anticorps (C-Term)

N° du produit ABIN2857033

Cet anticorps Lapin Polyclonal détecte spécifiquement ALDH1A1 dans WB, IF, IHC (p) et ICC. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour ALDH1A1 anticorps (C-Term) (ABIN2857033)

Antigène: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALDH1A1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Détail du produit anti-ALDH1A1 anticorps

Épitope: C-Term

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to ALDH1A1 (aldehyde dehydrogenase 1 family, member A1)
ALDH1A1 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ALDH1A1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A549 , mouse liver

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-ALDH1A1 (ABIN2857033)

Feng, Liu, Bian, Zhou, Liu: "ALDH1A3 affects colon cancer in vitro proliferation and invasion depending on CXCR4 status." dans: British journal of cancer, Vol. 118, Issue 2, pp. 224-232, (2019) (PubMed).

Détails sur ALDH1A1

Antigène: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Autre désignation: aldehyde dehydrogenase 1 family member A1

Sujet: This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes.

Cellular Localization: Cytoplasm

Poids moléculaire: 55 kDa

ID gène: 216

UniProt: P00352

Pathways: Dopaminergic Neurogenesis