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ALDH1A1 anticorps (C-Term)

ALDH1A1 Reactivité: Humain WB, IF, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2857033
  • Antigène Voir toutes ALDH1A1 Anticorps
    ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
    Épitope
    • 16
    • 13
    • 11
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 113
    • 52
    • 31
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 86
    • 33
    • 3
    Lapin
    Clonalité
    • 78
    • 44
    Polyclonal
    Conjugué
    • 60
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ALDH1A1 est non-conjugé
    Application
    • 95
    • 52
    • 45
    • 40
    • 34
    • 19
    • 18
    • 15
    • 14
    • 14
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Rabbit Polyclonal antibody to ALDH1A1 (aldehyde dehydrogenase 1 family, member A1)
    ALDH1A1 antibody [C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ALDH1A1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product ALDH1A1 Anticorps primaire
  • Indications d'application
    WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: A549 , mouse liver

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Feng, Liu, Bian, Zhou, Liu: "ALDH1A3 affects colon cancer in vitro proliferation and invasion depending on CXCR4 status." dans: British journal of cancer, Vol. 118, Issue 2, pp. 224-232, (2019) (PubMed).

  • Antigène
    ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
    Autre désignation
    aldehyde dehydrogenase 1 family member A1 (ALDH1A1 Produits)
    Synonymes
    anticorps ALDC, anticorps ALDH-E1, anticorps ALDH1, anticorps ALDH11, anticorps PUMB1, anticorps RALDH1, anticorps AL1A1, anticorps aldc, anticorps aldh-e1, anticorps aldh1, anticorps aldh11, anticorps pumb1, anticorps raldh1, anticorps GGADHR, anticorps ALDH1A1, anticorps ALDDH, anticorps Ahd2, anticorps Aldh1, anticorps Aldh2, anticorps Ahd-2, anticorps Aldh1a2, anticorps E1, anticorps Raldh1, anticorps Aldh1a1, anticorps ALHDII, anticorps RALDH 1, anticorps RalDH1, anticorps aldehyde dehydrogenase 1 family member A1, anticorps aldehyde dehydrogenase 1 family, member A1, anticorps aldehyde dehydrogenase 1 family member A1 L homeolog, anticorps aldehyde dehydrogenase family 1, subfamily A1, anticorps aldehyde dehydrogenase, anticorps retinal dehydrogenase 1, anticorps ALDH1A1, anticorps aldh1a1, anticorps Aldh1a1, anticorps aldh1a1.L, anticorps aldH1, anticorps LOC100732581, anticorps LOC101822890
    Sujet
    This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes.

    Cellular Localization: Cytoplasm
    Poids moléculaire
    55 kDa
    ID gène
    216
    UniProt
    P00352
    Pathways
    Dopaminergic Neurogenesis
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