PDGF antibody was raised in goat using purified human PDGF-AB as the immunogen.
Isotype
IgG
Indications d'application
Optimal conditions should be determined byt he investigator.
Restrictions
For Research Use only
Concentration
Lot specific
Buffer
Affi-Gel Blue purified protein supplied in 0.1 M tris-glycine, pH 7.0.
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Stock
-20 °C
Stockage commentaire
Aliquot and store at -20 °C.
Antigène
PDGF
Sujet
Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.