Rotavirus (RV) anticorps

N° du produit ABIN2859489

Cet anticorps Souris Monoclonal détecte spécifiquement Rotavirus dans WB et EIA. Il présente une réactivité avec des échantillons de Rotavirus.

Aperçu rapide pour Rotavirus (RV) anticorps (ABIN2859489)

Antigène: Rotavirus (RV)

Reactivité: Rotavirus

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 521

Détail du produit

Purification: Protein A chromatography.

Immunogène: Strain MR bovine rotavirus

Isotype: IgG2

Information d'application

Indications d'application: Suitable for use in ELISA and Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL (OD280 nm, E0.1% = 1.3)

Buffer: 0.01 M PBS, pH 7.2 containing 0.09 % sodium azide as preservative and no stabilizers.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détail du antigène

Antigène: Rotavirus (RV)

Autre désignation: Rotavirus

Classe de substances: Virus

Sujet: Rotaviruses, members of the family Reoviridae, are a major cause of diarrhoea in young mammals. Rotavirus infections also result in economic losses in agriculture due to diarrhoea in calf, pig, sheep, and poultry rearing. Diarrhoea (or scours) due to the rotavirus Nebraska Calf Diarrhea Virus can affect calves up to 30 days of age or older. Diarrhoea begins 2 to 3 days after exposure. Diagnosis is by history, lesions (ulcers on the tongue, lips, and mouth) and diagnostic laboratory tests. Mortality rates may be as high as 50 percent, depending on the secondary bacteria present. Human rotaviruses, the major aetiological agents of severe infantile diarrhoea worldwide, display surprisingly diverse and complex serotypic specificities. Rotaviruses are 70 nm, non enveloped viruses comprised of a triple layered protein capsid, Outer capsid proteins are VP4 and VP7, Inner capsid -VP6 and Core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection, therefore, multiple serotypes of rotavirus mean multiple opportunities for infection. The combination of animal reservoirs for the virus and rotavirus gene reassortment provides the potential for dramatic genetic shifts (similar to influenza virus) which could give rise to altered host ranges and viral virulence.