Shiga-like Toxin (Stx) (Subunit A) anticorps

N° du produit ABIN2859493

Cet anticorps Souris Monoclonal détecte spécifiquement dans EIA et Neut. Il présente une réactivité envers E. coli.

Aperçu rapide pour Shiga-like Toxin (Stx) (Subunit A) anticorps (ABIN2859493)

Antigène: Shiga-like Toxin (Stx)

Reactivité: E. coli

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Enzyme Immunoassay (EIA), Neutralization (Neut)

Clone: 557

Détail du produit

Épitope: Subunit A

Purification: Protein A affinity chromatography

Pureté: > 90 % pure

Isotype: IgG2

Information d'application

Indications d'application: ELISA. Neutralization.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL ( OD280nm, E0.1% = 1.4)

Buffer: 0.01 M PBS, pH 7.2, containing 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, aliquot and store at -20 °C.

Détail du antigène

Antigène: Shiga-like Toxin (Stx)

Sujet: Verotoxins are produced by certain enterohaemorrhagic strains of Escherichia coli. Serotype O157:H7 has been the strain most commonly associated with large food bourne outbreaks and has been implicated in a wide spectrum of diseases including blood diarrhoea, haemorrhagic colitis and haemolytic uraemic syndrome. The main sources of infection are contaminated foods of animal origin such as meat and dairy products. Verotoxins, also called Shiga like toxins( SLT) because of their similarity to toxins produced by Shigella dysenteriae, are classified into two main categories: verotoxin 1 (VT1, SLT1, Stx1) and 2 (VT2, SLT2, Stx2). Verotoxin production is the most common criteria for the detection of this group of bacteria rather than tests for the cytopathic effect on Vero cells that gave the toxins their name. Verotoxins contain a single A subunit and multiple copies of a B subunit. The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits.Synonyms: SLT-2 A subunit, SLT-2a, SLT-IIa, Verocytotoxin 2 subunit A, Verotoxin 2 subunit A, rRNA N-glycosidase 2, stx2A, stxA2

ID gène: 10730

UniProt: P09385