HCV Core Protein anticorps

N° du produit ABIN2859553

Cet anticorps Souris Monoclonal détecte spécifiquement HCV Core Protein dans EIA. Il présente une réactivité avec des échantillons de Hepatitis C Virus (HCV).

Aperçu rapide pour HCV Core Protein anticorps (ABIN2859553)

Antigène: HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))

Reactivité: Hepatitis C Virus (HCV)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HCV Core Protein est non-conjugé

Application: Enzyme Immunoassay (EIA)

Clone: B055M

Détail du produit anti-HCV Core Protein anticorps

Attributs du produit: Synonyms: Hepatitis C Virus

Purification: Protein A chromatography

Pureté: > 90 % pure

Immunogène: Recombinant HCV core antigen, genotype 1a

Isotype: IgG2a

Information d'application

Indications d'application: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,1 mg/mL (OD280nm, E0.1% = 1.4)

Buffer: 0.01 M PBS, pH 7.2 containing 0,09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur HCV Core Protein

Antigène: HCV Core Protein (HCV C) (Hepatitis C Virus Core Protein (HCV C))

Autre désignation: HCV Core Protein

Classe de substances: Viral Protein

Sujet: The hepatitis C virus (HCV) core protein represents the first 191 amino acids of the viral precursor polyprotein and is cotranslationally inserted into the membrane of the endoplasmic reticulum. Hepatitis C virus (HCV) core is a viral structural protein, it also participates in some cellular processes, including transcriptional regulation. However the mechanisms of core-mediated transcriptional regulation remain poorly understood. Hepatitis C virus (HCV) core protein is thought to contribute to HCV pathogenesis through its interaction with various signal transduction pathways. In addition, HCV core antigen is a recently developed marker of hepatitis C infection. The HCV core protein has been previously shown to circulate in the bloodstream of HCV-infected patients and inhibit host immunity through an interaction with gC1qR. Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Hepatitis C virus (HCV) causes most cases of non-A, non-B hepatitis and results in most HCV infected people developing chronic infections, liver cirrhosis and hepatocellular carcinoma. T cell responses, including interferon-gamma production are severely suppressed in chronic HCV patients.Synonyms: Hepatitis C Virus core protein