UVRAG anticorps (Biotin)

N° du produit ABIN2868821

Cet anticorps Lapin Polyclonal détecte spécifiquement UVRAG dans WB, IF et ICC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour UVRAG anticorps (Biotin) (ABIN2868821)

Antigène: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UVRAG est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-UVRAG anticorps (Biotin)

Specificité: Predicted molecular weight at ~78.1 kDa. Observed molecular weights in the 75-90 kDa range.

Réactivité croisée: Humain, Souris, Rat

Purification: Peptide Affinity Purified

Immunogène: Synthetic peptide from the mid-protein of human UVRAG

Information d'application

Indications d'application:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Commentaires:

A 1:1000 dilution of ABIN2868821 was sufficient for detection of UVRAG on HeLa cell lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur UVRAG

Antigène: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Autre désignation: UVRAG

Sujet: UVRAG (UV radiation resistance-associated gene) is associated with the Beclin-1/PI3KC3 complex and promotes PI3KC3 enzymatic activity and autophagy, while suppressing proliferation (1). Beclin-1 binding to UVRAG promotes both autophagosome maturation and endocytic trafficking (2). UVRAG is also a potential tumor suppressor protein with frameshift mutations observed in colon and gastric carcinomas (3-4). It is highly expressed in the brain, lung, kidney and liver.

ID gène: 7405

NCBI Accession: NP_003360

UniProt: Q9P2Y5