PGE2 anticorps

N° du produit ABIN2869135

Cet anticorps anti-PGE2 est un anticorps Souris Monoclonal détectant PGE2 dans IA. Adapté pour Humain.

Aperçu rapide pour PGE2 anticorps (ABIN2869135)

Antigène: PGE2 (Prostaglandin E2 (PGE2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PGE2 est non-conjugé

Application: Immunoassay (IA)

Clone: 5A2

Détail du produit anti-PGE2 anticorps

Immunogène: PGE2 covalently coupled to carrier protein

Information d'application

Indications d'application: For Immunoassay Use

Commentaires:

Mouse Monoclonal to Prostaglandin E2 (PGE2) Extend primary antibody supplies Clone 5A2

Restrictions: For Research Use only

Stockage

Buffer: 100 mM Sodium Phosphate, 150 mM Sodium Chloride, 0.09 % Na Azide, pH 7.2

Détails sur PGE2

Antigène: PGE2 (Prostaglandin E2 (PGE2))

Autre désignation: Prostaglandin E2

Sujet: Eicosanoid signal transduction pathways are highly conserved and are involved in a number of physiological processes. Prostaglandins are synthesized from arachidonic acid by cyclooxygenase (COX)-1 or -2, which con- vert the acid into PGH2. This is further processed by cytosolic or microsomal prostaglandin synthases to become PGE2 or one of several other prostanoids. Prostacyclin is the major cyclooxygenase product in blood vessel walls and it is present in inflammatory fluids in similar concentrations to PGE2. Prostacyclin is a potent vasodilator and is more potent than PGE2 in producing hyperalgesia. PGE2 is produced by a wide variety of tissues and in several pathological conditions, including inflammation, arthritis, fever, tissue injury, endometriosis, and a variety of cancers. Other biological actions of PGE2 include vasodilation, modulation of sleep/wake cycles, and facilitation of human immunodeficiency virus replication. It elevates cAMP levels, stimulates bone resorption, and has thermoregula- tory effects. It has been shown to be a regulator of sodium excretion and renal hemodynamics.