UCP2 anticorps

N° du produit ABIN289564

Détail du produit anti-UCP2 anticorps

Antigène: UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UCP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Specificité: This antibody reacts with residues 125-142 EETAKKVRRAIEQLAAMD of the human Survivin protein. Cross reacts with mouse and rat Survivin (88% sequenceidentity).

Réactivité croisée (Details): This UCP2 peptide sequence is 100 % conserved in rat, hamster, and 86 % in human, pig, canine, and bovine UCP2. It has no significant homology with UCP1, UCP3-5.

Purification: Affinity chromatography purified

Immunogène: UCP2 antibody was raised in rabbit using a 14 amino acid peptide from mouse UCP2 as the immunogen.

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1:10,000-1:100,000, HC: 2-20 µg/mL, IF: 2-20 µg/mL, WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in PBS to a concentraiton of 1 mg/mL.

Concentration: Lot specific

Buffer: Affinity purified antibody lyophilized from PBS with 0.1 % BSA.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Détails sur UCP2

Antigène: UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))

Autre désignation: UCP2 (UCP2 Produits)

Synonymes: anticorps UCP2, anticorps DKFZp470P1633, anticorps ucp2, anticorps MGC53319, anticorps MGC75881, anticorps cb74, anticorps ATUCP2, anticorps K19M22.21, anticorps K19M22_21, anticorps uncoupling protein 2, anticorps BMIQ4, anticorps SLC25A8, anticorps UCPH, anticorps Slc25a8, anticorps mitochondrial uncoupling protein 2, anticorps uncoupling protein 2, anticorps uncoupling protein 2 (mitochondrial, proton carrier) L homeolog, anticorps uncoupling protein 2 (mitochondrial, proton carrier), anticorps uncoupling protein 1, anticorps PTRG_09289, anticorps UCP2, anticorps LOC100282746, anticorps ucp2.L, anticorps ucp2, anticorps ucp1, anticorps Ucp2

Sujet: Uncoupling proteins (UCP1-5) are a family of mitochondria transport proteins that play a critical role in thermoregulatory heat production and maintenance of basal metabolic rate. UCP3 is predicted to contain 6 transmembrane domains. The UCP3S lacks the 6th transmembrane domain and it is only 275 aa long. Mouse/rat UCP2 is A 309 AA (human 309 aa chromosome 7, ~95% homology) mitochondrial uncoupling protein. UCP2 has wide tissue distribution in mouse tissues (brain, kidney, liver, brown adipose tissue, heart, and muscle). UCP2 may play a critical role in energy balance, body weight, and thermoregulation.

Pathways: Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Proton Transport