TNNI3 anticorps

N° du produit ABIN295183

Cet anticorps Chèvre Polyclonal détecte spécifiquement TNNI3 dans ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TNNI3 anticorps (ABIN295183)

Antigène: TNNI3 (Cardiac Troponin I (TNNI3))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNI3 est non-conjugé

Application: ELISA

Détail du produit anti-TNNI3 anticorps

Specificité: Recognizes human cardiac-specific troponin I, (TnI) an integral inhibitory protein of cardiac muscle which exists as a complex with troponin C (TnC) and troponin T (TnT). The TnT subunit of troponin binds to tropomyosin to form a troponin-tropomyosin complex, anchored in place by the binding of TnI to actin, within muscle thin filaments. Structural change resulting from the binding of calcium to specific sites on the regulatory TnC subunit, releases the inhibitory region of TnI from actin, enabling the attachment of the molecular motor protein myosin, allowing for muscle contraction and hence movement. The measurement of blood TnI and TnT levels is an important diagnostic indicator of heart muscle damage, and can be used to differentiate between angina and myocardic infarction in patients with chest pain. Troponin I has also been shown to inhibit angiogenesis in vivo and in vitro.

Purification: Affinity purified

Immunogène: Native human cardiac troponin I, purity greater than 98%.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur TNNI3

Antigène: TNNI3 (Cardiac Troponin I (TNNI3))

Autre désignation: TNNI3 / CTnI

Sujet: Name/Gene ID: TNNI3

Synonyms: TNNI3, CTnI, CMD1FF, CMD2A, RCM1, Troponin I, cardiac, Troponin I, cardiac muscle, Troponin I type 3 (cardiac), Cardiac troponin I, CMH7

ID gène: 7137

UniProt: P19429