Cet anticorps Souris Monoclonal détecte spécifiquement beta Amyloid 1-16 dans WB, IF, IP, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.
Working dilution: Optimal dilution should be determined by the end user. The following are guidelines only: 1 - 10 μg/mL for any applications
Restrictions
For Research Use only
Buffer
PBS, pH 7.4.
Conseil sur la manipulation
Dilute in PBS or medium which is identical to that used in the assay system.
Stock
-20 °C
Stockage commentaire
Stable for at least one year at -20°C
Date de péremption
12 months
Antigène
beta Amyloid 1-16
Autre désignation
Amyloid beta 1-16
Sujet
Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). There is now compelling evidence that metal binding to Aβ is involved in AD pathogenesis. The amino acid region 1-16 is widely considered as the metal binding domain of Aβ. Unlike copper(II) that prefers the N-terminal amino group as the main binding site, zinc(II) is preferentially placed in the 8-16 amino acidic region of Aβ (1-16).