beta Amyloid 1-16 anticorps

N° du produit ABIN2961825

Détail du produit

Antigène: beta Amyloid 1-16

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA

Specificité: Reacts with humanand mouse Aβ1-16 as well as other Aβ peptides: Aβ37, Aβ38, Aβ39, Aβ40 and Aβ42

Purification: Purified

Immunogène: Synthetic peptide corresponding to Abeta1-16.

Clone: Ab3

Isotype: IgG1

Information d'application

Indications d'application: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
1 - 10 μg/mL for any applications

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.4.

Conseil sur la manipulation: Dilute in PBS or medium which is identical to that used in the assay system.

Stock: -20 °C

Stockage commentaire: Stable for at least one year at -20°C

Date de péremption: 12 months

Détail du antigène

Antigène: beta Amyloid 1-16

Autre désignation: Amyloid beta 1-16

Sujet: Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). There is now compelling evidence that metal binding to Aβ is involved in AD pathogenesis. The amino acid region 1-16 is widely considered as the metal binding domain of Aβ. Unlike copper(II) that prefers the N-terminal amino group as the main binding site, zinc(II) is preferentially placed in the 8-16 amino acidic region of Aβ (1-16).

Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Gene name: APP, A4, AD1

ID gène: 351

UniProt: P05067