ICAM2 anticorps
Aperçu rapide pour ICAM2 anticorps (ABIN2967162)
Antigène
Voir toutes ICAM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-Hu CD102 Purified
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Réactivité croisée (Details)
- Human
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Attributs du produit
- The mouse monoclonal antibody CBR-IC2/2 recognizes an extracellular epitope of CD102 (ICAM-2), an approximately 55 kDa type I transmembrane glycoprotein expressed mainly on vascular endothelial cells and folicular dendritic cells, in lower amount on lymphocytes, monocytes and platelets.
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Purification
- Purified by protein-A affinity chromatography.
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Pureté
- > 95 % (by SDS-PAGE)
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Immunogène
- Human CD102 cDNA transfected COS cells
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Isotype
- IgG2a
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Indications d'application
- Flow cytometry: Recommended dilution: 2-4 μg/mL.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
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Autre désignation
- CD102
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Sujet
- Intercellular adhesion molecule 2,CD102 / ICAM-2 (intracellular cell adhesion molecule-2), a counter receptor of LFA-1 (CD11a/CD18), is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes, monocytes, thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration.,ICAM2
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ID gène
- 3384
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UniProt
- P13598
Antigène
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