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CD39 anticorps (PE)

ENTPD1 Reactivité: Humain FACS Hôte: Souris Monoclonal TU66 PE
N° du produit ABIN2967171
  • Antigène Voir toutes CD39 (ENTPD1) Anticorps
    CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
    Reactivité
    • 73
    • 37
    • 25
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 41
    • 34
    • 9
    • 1
    • 1
    Souris
    Clonalité
    • 50
    • 36
    Monoclonal
    Conjugué
    • 41
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD39 est conjugé à/à la PE
    Application
    • 37
    • 36
    • 21
    • 15
    • 11
    • 9
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody TU66, also known as Tü66, recognizes an extracellular epitope of CD39, a 78 kDa cell surface enzyme expressed by regulatory T cells, mantle zone B cells, activated T cells, NK cells, macrophages, dendritic cells, neurons, endothelial cells and platelets.
    Réactivité croisée (Details)
    Human
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Clone
    TU66
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product ENTPD1 Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Commentaires

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène
    CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
    Autre désignation
    CD39 (ENTPD1 Produits)
    Synonymes
    anticorps ATPDase, anticorps CD39, anticorps NTPDase-1, anticorps MGC80631, anticorps zgc:100819, anticorps entpd1, anticorps MGC79567, anticorps 2610206B08Rik, anticorps AA408691, anticorps Cd39, anticorps ectonucleoside triphosphate diphosphohydrolase 1, anticorps ectonucleoside triphosphate diphosphohydrolase 1 L homeolog, anticorps ENTPD1, anticorps Entpd1, anticorps entpd1.L, anticorps entpd1
    Sujet
    Ectonucleoside triphosphate diphosphohydrolase 1,CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1), is a cell surface enzyme (with intracellular N- and C-terminus) which hydrolyzes extracellular ATP and ADP to AMP. Inhibition of its enzymatic activity may confer anticancer benefits. The formation of oligomers in the plasma membrane is essential for enzyme activity. It is expressed on Treg cells, and in other cell types, such as mantle zone B cells, activated T cells, NK cells, macrophages, dendritic cells, neurons, endothelial cells and platelets. Hydrolysis of ATP and ADP inhibits inflammatory and thrombotic responses. In the nervous system, it regulates purinergic neurotransmission.,ETDH1, LCAA, Ecto-ATPase 1, Ecto-apyrase, ENTPD1
    ID gène
    953
    UniProt
    P49961
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