IKZF1 anticorps (C-Term)
Aperçu rapide pour IKZF1 anticorps (C-Term) (ABIN2967181)
Antigène
Voir toutes IKZF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- C-Term
-
Fonction
- Anti-Ikaros Purified
-
Réactivité croisée (Details)
- Human, Mouse
-
Attributs du produit
- The mouse monoclonal antibody 4E9 recognizes Ikaros, a transcription factor (intracellular antigen) expressed broadly in hematopoietic progenitors and serving as a key regulator of lymphopoiesis.
-
Purification
- Purified by protein-A affinity chromatography.
-
Pureté
- > 95 % (by SDS-PAGE)
-
Immunogène
- Recombinant human Ikaros (C-terminal part)
-
Isotype
- IgG1
-
-
-
-
Indications d'application
- Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Do not freeze
-
Stock
- 4 °C
-
Stockage commentaire
- Store at 2-8°C. Do not freeze.
-
-
- IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))
-
Autre désignation
- Ikaros
-
Sujet
- IKAROS family zinc finger 1,Ikaros, also known as IKZF1 (Ikaros family zinc finger protein 1) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development, together with other members of this family, such as Aiolos and Helios. Ikaros forms homo- and heterodimers with these proteins and functions predominantly in early hematopoietic development. Expression of Ikaros, Aiolos and Helios is restricted to cells of the hematopoietic system, whereas other family members, Eos and Pegassus, are more widely expressed. Disruption of Ikaros leads to T and B cell leukemias.,IKZF1, IK1, LYF1, LyF-1, IKAROS, PPP1R92, PRO0758, ZNFN1A1, Hs.54452, IKAROS family zinc finger 1, Lymphoid transcription factor LyF-1
-
ID gène
- 10320
-
UniProt
- Q13422
-
Pathways
- Production of Molecular Mediator of Immune Response
Antigène
-