TACR3 anticorps

N° du produit ABIN298071

Cet anticorps anti-TACR3 Polyclonal Lapin (ABIN298071) détecte spécifiquement TACR3 dans WB, IHC et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour TACR3 anticorps (ABIN298071)

Antigène: TACR3 (Tachykinin Receptor 3 (TACR3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TACR3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TACR3 anticorps

Specificité: Recognizes human TACR3 otherwise known as NK3 Receptor (NK3R), a 52.2 kD multi-pass membrane protein belonging to the G-protein coupled receptor 1 family. TACR3 is a receptor for the tachykinin neuropeptide, neuromedin-k otherwise known as neurokinin B and is highly expressed in the supraoptic and paraventricular nuclei. Following binding of its ligand, NK3R activates a phosphatidylinositol-calcium second messenger system, and it is likely that these signals lead to the release of vasopressin and oxytocin into the circulation. Studies with mice indicate that TACR3 is involved in learning and memory. AHP1492 does not recognize NK1R or NK2R.

Purification: Affinity purified

Immunogène: An 18 amino acid peptide from near the center of human TACR3.

Information d'application

Indications d'application: Approved: IHC, IHC-P (5 μg/mL), WB (0.5 - 1 μg/mL)

Usage: Western Blot: LS-C56946 detects a band of approximately 46kD in RAW264.7 cell lysates. Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Short term: -20°C
Long term: -20°C.

Détails sur TACR3

Antigène: TACR3 (Tachykinin Receptor 3 (TACR3))

Autre désignation: TACR3 / NK3R

Sujet: Name/Gene ID: TACR3
Subfamily: Tachykinin
Family: GPCR

Synonyms: TACR3, HH11, Nmk-r, NK3R, NKR, Tachykinin receptor 3, Neurokinin B, Neurokinin B receptor, NK-3 receptor, NK-3R, TAC3R, Neurokinin 3 receptor, Neurokinin beta receptor, Neuromedin-K receptor, TAC3RL

ID gène: 6870

UniProt: P29371

Pathways: Feeding Behaviour