CHD3 anticorps
Aperçu rapide pour CHD3 anticorps (ABIN2983311)
Antigène
Voir toutes CHD3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Immunogène
- Purified recombinant fragment of human CHD3 expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
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Autre désignation
- CHD3
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Sujet
- This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
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Poids moléculaire
- 226 kDa
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ID gène
- 1107
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UniProt
- Q12873
Antigène
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