SLC44A1 anticorps (C-Term) (FITC)
Aperçu rapide pour SLC44A1 anticorps (C-Term) (FITC) (ABIN298883)
Antigène
Voir toutes SLC44A1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- C-Term
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Specificité
- Specific for the C-terminal variant of human CDw92 (isoform 3), also known as CTL1, a 70kD multi-pass membrane protein, expressed by monocytes, neutrophils, certain myeloid and T cell lines, and weakly by endothelial cells, fibroblasts and epithelial cells. CDw92 is a member of the choline transporter-like protein family, so called due to their involvement in the efficient supply/transport of the natural amine choline, a vital cell nutrient required for the synthesis of cell membrane phospholipid components and the neurotransmitter acetylcholine. Clone VIM-15b is reported to augment the LPS-induced production of IL-10 by monocyte-derived dendritic cells (Mo-DCs), and the reduced expression of CDw92 by Mo-DCs treated with ionomycin or calcium ionophore, can be reinduced in the presence of IL-10.
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Purification
- Affinity purified
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Immunogène
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MV4-11 acute monocyte leukaemia cells.
Type of Immunogen: Cells -
Isotype
- IgG2b
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Indications d'application
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Approved: Flo (1:1 - 1:5), IHC, IHC-Fr, IP
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- SLC44A1 (Solute Carrier Family 44, Member 1 (SLC44A1))
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Autre désignation
- SLC44A1 / CD92
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Sujet
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Name/Gene ID: SLC44A1
Subfamily: Choline transporter-like
Family: Transporter
Synonyms: SLC44A1, CD92 antigen, CTL1, RP11-287A8.1, CD92, CDW92, CDW92 antigen, CHTL1 -
ID gène
- 23446
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UniProt
- Q8WWI5
Antigène
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