Glutamate Receptor 1 anticorps (AA 19-300)

N° du produit ABIN3015589

Cet anticorps Lapin Polyclonal détecte spécifiquement Glutamate Receptor 1 dans WB, IHC et IF. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour Glutamate Receptor 1 anticorps (AA 19-300) (ABIN3015589)

Antigène: Glutamate Receptor 1 (GLUR1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutamate Receptor 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Glutamate Receptor 1 anticorps

Épitope: AA 19-300

Séquence: ANFPNNIQIG GLFPNQQSQE HAAFRFALSQ LTEPPKLLPQ IDIVNISDSF EMTYRFCSQF SKGVYAIFGF YERRTVNMLT SFCGALHVCF ITPSFPVDTS NQFVLQLRPE LQDALISIID HYKWQKFVYI YDADRGLSVL QKVLDTAAEK NWQVTAVNIL TTTEEGYRML FQDLEKKKER LVVVDCESER LNAILGQIIK LEKNGIGYHY ILANLGFMDI DLNKFKESGA NVTGFQLVNY TDTIPAKIMQ QWKNSDARDH TRVDWKRPKY TSALTYDGVK VM

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 19-300 of human GluR1/GluR1/GRIA1 (NP_000818.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Glutamate Receptor 1 (ABIN3015589)

Liu, Feng, Chen, Luo, Yan, Chen, Lin, Ding, Wen: "Dcf1 Triggers Dendritic Spine Formation and Facilitates Memory Acquisition." dans: Molecular neurobiology, Vol. 55, Issue 1, pp. 763-775, (2018) (PubMed).

Détails sur Glutamate Receptor 1

Antigène: Glutamate Receptor 1 (GLUR1)

Autre désignation: GRIA1

Sujet: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,GRIA1,GLUH1,GLUR1,GLURA,GluA1,HBGR1,GluR1,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Dopamine Signaling in Parkinson's Disease,GRIA1

Poids moléculaire: 92 kDa/93 kDa/101 kDa/102 kDa

ID gène: 2890

UniProt: P42261

Pathways: Signalisation PI3K-Akt