Chitotriosidase 1 anticorps (AA 217-466)

N° du produit ABIN3015833

Cet anticorps Lapin Polyclonal détecte spécifiquement Chitotriosidase 1 dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour Chitotriosidase 1 anticorps (AA 217-466) (ABIN3015833)

Antigène: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Chitotriosidase 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Chitotriosidase 1 anticorps

Épitope: AA 217-466

Séquence: SWEKVTGHNS PLYKRQEESG AAASLNVDAA VQQWLQKGTP ASKLILGMPT YGRSFTLASS SDTRVGAPAT GSGTPGPFTK EGGMLAYYEV CSWKGATKQR IQDQKVPYIF RDNQWVGFDD VESFKTKVSY LKQKGLGGAM VWALDLDDFA GFSCNQGRYP LIQTLRQELS LPYLPSGTPE LEVPKPGQPS EPEHGPSPGQ DTFCQGKADG LYPNPRERSS FYSCAAGRLF QQSCPTGLVF SNSCKCCTWN

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 217-466 of human CHIT1 (NP_003456.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Chitotriosidase 1

Antigène: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Autre désignation: CHIT1

Sujet: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.,CHIT1,CHI3,CHIT,CHITD,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CHIT1

Poids moléculaire: 43 kDa/48 kDa/49 kDa/51 kDa

ID gène: 1118

UniProt: Q13231