Mps1 anticorps (AA 517-856)

N° du produit ABIN3016144

Cet anticorps Lapin Polyclonal détecte spécifiquement Mps1 dans WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour Mps1 anticorps (AA 517-856) (ABIN3016144)

Antigène: Mps1 (TTK)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mps1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Mps1 anticorps

Épitope: AA 517-856

Séquence: ISVKGRIYSI LKQIGSGGSS KVFQVLNEKK QIYAIKYVNL EEADNQTLDS YRNEIAYLNK LQQHSDKIIR LYDYEITDQY IYMVMECGNI DLNSWLKKKK SIDPWERKSY WKNMLEAVHT IHQHGIVHSD LKPANFLIVD GMLKLIDFGI ANQMQPDTTS VVKDSQVGTV NYMPPEAIKD MSSSRENGKS KSKISPKSDV WSLGCILYYM TYGKTPFQQI INQISKLHAI IDPNHEIEFP DIPEKDLQDV LKCCLKRDPK QRISIPELLA HPYVQIQTHP VNQMAKGTTE EMKYVLGQLV GLNSPNSILK AAKTLYEHYS GGESHNSSSS KTFEKKRGKK

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 517-856 of human TTK (NP_001160163.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Mps1

Antigène: Mps1 (TTK)

Autre désignation: TTK

Sujet: This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.,TTK,CT96,ESK,MPH1,MPS1,MPS1L1,PYT,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centromere,TTK

Poids moléculaire: 96 kDa/97 kDa

ID gène: 7272

UniProt: P33981