OPCML anticorps (AA 246-345)
Aperçu rapide pour OPCML anticorps (AA 246-345) (ABIN3016672)
Antigène
Voir toutes OPCML AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 246-345
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Séquence
- ASAVPMAEFQ WFKEETRLAT GLDGMRIENK GRMSTLTFFN VSEKDYGNYT CVATNKLGNT NASITLYGPG AVIDGVNSAS RALACLWLSG TLLAHFFIKF
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 246-345 of human OPCML (NP_002536.1).
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Isotype
- IgG
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Indications d'application
- WB,1:1000 - 1:2000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- OPCML (Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))
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Autre désignation
- OPCML
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Sujet
- This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,OPCML,IGLON1,OBCAM,OPCM,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Cell Adhesion,Neuroscience,OPCML
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Poids moléculaire
- 33 kDa/37 kDa/38 kDa
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ID gène
- 4978
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UniProt
- Q14982
Antigène
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