PGC anticorps (AA 100-200)

N° du produit ABIN3016695

Cet anticorps Lapin Polyclonal détecte spécifiquement PGC dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour PGC anticorps (AA 100-200) (ABIN3016695)

Antigène: PGC (Pepsinogen C (PGC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PGC anticorps

Épitope: AA 100-200

Séquence: PSVYCQSQAC TSHSRFNPSE SSTYSTNGQT FSLQYGSGSL TGFFGYDTLT VQSIQVPNQE FGLSENEPGT NFVYAQFDGI MGLAYPALSV DEATTAMQGM V

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Pepsinogen II (NP_001159896.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PGC

Antigène: PGC (Pepsinogen C (PGC))

Autre désignation: PGC

Sujet: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.,PGC,PEPC,PGII,gastricsin,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,PGC

Poids moléculaire: 34 kDa/42 kDa

ID gène: 5225

UniProt: P20142