Acetylcholinesterase anticorps (AA 398-617)

N° du produit ABIN3016743

Détail du produit anti-Acetylcholinesterase anticorps

Antigène: Acetylcholinesterase (AChE)

Épitope: AA 398-617

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acetylcholinesterase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: VPQVSDLAAE AVVLHYTDWL HPEDPARLRE ALSDVVGDHN VVCPVAQLAG RLAAQGARVY AYVFEHRAST LSWPLWMGVP HGYEIEFIFG IPLDPSRNYT AEEKIFAQRL MRYWANFART GDPNEPRDPK APQWPPYTAG AQQYVSLDLR PLEVRRGLRA QACAFWNRFL PKLLSATASE APSTCPGFTH GEAAPRPGLP LPLLLLHQLL LLFLSHLRRL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 398-617 of human ACHE (NP_056646.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Acetylcholinesterase

Antigène: Acetylcholinesterase (AChE)

Autre désignation: ACHE (AChE Produits)

Synonymes: anticorps ACEE, anticorps ARACHE, anticorps N-ACHE, anticorps YT, anticorps Ache, anticorps GB14873, anticorps zgc:92550, anticorps ACE, anticorps Dsim\\GD20515, anticorps GD20515, anticorps dsim_GLEANR_4292, anticorps ache, anticorps mE1a, anticorps mE1b, anticorps mE1c, anticorps mE1c-long, anticorps mE1d, anticorps mE1d', anticorps mE1e, anticorps arache, anticorps n-ache, anticorps acetylcholinesterase (Cartwright blood group), anticorps acetylcholinesterase 2, anticorps acetylcholinesterase, anticorps Acetylcholine esterase, anticorps acetylcholinesterase (Cartwright blood group) L homeolog, anticorps collagen type I alpha 2 chain, anticorps ACHE, anticorps AChE-2, anticorps Ache, anticorps ache, anticorps Dsim\Ace, anticorps ache.L, anticorps COL1A2, anticorps ACE-1

Sujet: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.,ACHE,ACEE,ARACHE,N-ACHE,YT,Neuroscience,ACHE

Poids moléculaire: 58 kDa/65 kDa/67 kDa

ID gène: 43

UniProt: P22303

Pathways: Skeletal Muscle Fiber Development