EIF4G2 anticorps (AA 750-850)

N° du produit ABIN3016941

Cet anticorps anti-EIF4G2 est un anticorps Lapin Polyclonal détectant EIF4G2 dans WB, IHC, IF et IP. Adapté pour Humain.

Aperçu rapide pour EIF4G2 anticorps (AA 750-850) (ABIN3016941)

Antigène: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF4G2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-EIF4G2 anticorps

Épitope: AA 750-850

Séquence: IYKWIKDNIS PKLHVDKGFV NILMTSFLQY ISSEVNPPSD ETDSSSAPSK EQLEQEKQLL LSFKPVMQKF LHDHVDLQVS ALYALQVHCY NSNFPKGMLL R

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 750-850 of human EIF4G2 (NP_001409.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000,IHC,1:100 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EIF4G2

Antigène: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Autre désignation: EIF4G2

Sujet: Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.,EIF4G2,AAG1,DAP5,NAT1,P97,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,EIF4G2

Poids moléculaire: 98 kDa/102 kDa

ID gène: 1982

UniProt: P78344