GRPR anticorps (AA 235-384)

N° du produit ABIN3017022

Cet anticorps Lapin Polyclonal détecte spécifiquement GRPR dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour GRPR anticorps (AA 235-384) (ABIN3017022)

Antigène: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRPR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GRPR anticorps

Épitope: AA 235-384

Séquence: KNLIQSAYNL PVEGNIHVKK QIESRKRLAK TVLVFVGLFA FCWLPNHVIY LYRSYHYSEV DTSMLHFVTS ICARLLAFTN SCVNPFALYL LSKSFRKQFN TQLLCCQPGL IIRSHSTGRS TTCMTSLKST NPSVATFSLI NGNICHERYV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 235-384 of human GRPR (NP_005305.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GRPR

Antigène: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Autre désignation: GRPR

Sujet: Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.,GRPR,BB2,BB2R,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,GRPR

Poids moléculaire: 43 kDa

ID gène: 2925

UniProt: P30550