L’anticorps Souris Monoclonal anti-CRP a été validé pour ELISA. Il convient pour détecter CRP dans des échantillons de Humain. Il y a 1 publication disponible.
The mouse monoclonal antibody C7 recognizes human CRP, a 117 kDa acute phase protein, it detects the antigen both in the presence and in the absence (samples containing EDTA) of Ca2+.
Réactivité croisée (Details)
Human
Purification
Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
CRP
Reactivité: Rat
WB, IHC, ICC, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Do not freeze. Avoid prolonged exposure to light.
Stock
4 °C
Stockage commentaire
Store at 2-8°C. Do not freeze.
Krämer, Kess, Kremmer, Schulte-Hostede: "Multi-parameter determination of TNF?, PCT and CRP for point-of-care testing." dans: The Analyst, Vol. 136, Issue 4, pp. 692-5, (2011) (PubMed).
Antigène
CRP
(C-Reactive Protein (CRP))
Autre désignation
CRP
Sujet
C-reactive protein,The C-reactive protein (CRP) is a cyclic pentameric pentraxin family acute phase protein composed of five identical noncovalently bound nonglycosylated subunits (each subunit 24 kDa, physiologic CRP molecule 117,5 kDa). CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes occuring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.) and is also believed to play an important role in innate immunity. Patients with elevated basal levels of CRP are at increased risk for hypertension and cardiovascular disease.