GFAP anticorps (C-Term)

N° du produit ABIN3020751

Cet anticorps Lapin Polyclonal détecte spécifiquement GFAP dans WB, IHC et IF. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour GFAP anticorps (C-Term) (ABIN3020751)

Antigène: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFAP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-GFAP anticorps

Épitope: C-Term

Séquence: RGTNESLERQ MREQEERHVR EAASYQEALA RLEEEGQSLK DEMARHLQEY QDLLNVKLAL DIEIATYRKL LEGEENRITI PVQTFSNLQI RETSLDTKSV SEGHLKRNIV VKTVEMRDGE VIKESKQEHK DVM

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human GFAP (NP_002046.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-GFAP (ABIN3020751)

Qiang, Jun-Jie, Hai, Hong, Bing-Xi, Lei, Wei, Ya-Wei, Huang, Song-Tao, Yun-Tao: "TPD52L2 impacts proliferation, invasiveness and apoptosis of glioblastoma cells via modulation of wnt/β-catenin/snail signaling." dans: Carcinogenesis, Vol. 39, Issue 2, pp. 214-224, (2018) (PubMed).

Yao, Weng, Zhang, Feng, Lin, Yao: "Interleukin-17A Acts to Maintain Neuropathic Pain Through Activation of CaMKII/CREB Signaling in Spinal Neurons." dans: Molecular neurobiology, Vol. 53, Issue 6, pp. 3914-3926, (2016) (PubMed).

Détails sur GFAP

Antigène: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Autre désignation: GFAP

Sujet: This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,ALXDRD,GFAP,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Intermediate Filaments,Neuroscience,Cell Type Marker,Stem Cells,Neural Stem Cells,Astrocyte marker,Microglia marker,GFAP

Poids moléculaire: 49 kDa/50 kDa

ID gène: 2670

UniProt: P14136