BMP7 anticorps (AA 132-431)
Aperçu rapide pour BMP7 anticorps (AA 132-431) (ABIN3021109)
Antigène
Voir toutes BMP7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 132-431
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Séquence
- MVMSFVNLVE HDKEFFHPRY HHREFRFDLS KIPEGEAVTA AEFRIYKDYI RERFDNETFR ISVYQVLQEH LGRESDLFLL DSRTLWASEE GWLVFDITAT SNHWVVNPRH NLGLQLSVET LDGQSINPKL AGLIGRHGPQ NKQPFMVAFF KATEVHFRSI RSTGSKQRSQ NRSKTPKNQE ALRMANVAEN SSSDQRQACK KHELYVSFRD LGWQDWIIAP EGYAAYYCEG ECAFPLNSYM NATNHAIVQT LVHFINPETV PKPCCAPTQL NAISVLYFDD SSNVILKKYR NMVVRACGCH
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 132-431 of human BMP7 (NP_001710.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- BMP7 (Bone Morphogenetic Protein 7 (BMP7))
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Autre désignation
- BMP7
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Sujet
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients.,BMP7,OP-1,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Cytoskeleton,Extracellular Matrix,Bone,Growth factor,TGF-b-Smad Signaling Pathway,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,Cytokines,NF-kB Signaling Pathway,Stem Cells,Ligand,BMP7
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Poids moléculaire
- 49 kDa
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ID gène
- 655
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UniProt
- P18075
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Pathways
- Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance
Antigène
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