PDIA3 anticorps (AA 206-505)
Aperçu rapide pour PDIA3 anticorps (AA 206-505) (ABIN3021400)
Antigène
Voir toutes PDIA3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 206-505
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Séquence
- FRPSHLTNKF EDKTVAYTEQ KMTSGKIKKF IQENIFGICP HMTEDNKDLI QGKDLLIAYY DVDYEKNAKG SNYWRNRVMM VAKKFLDAGH KLNFAVASRK TFSHELSDFG LESTAGEIPV VAIRTAKGEK FVMQEEFSRD GKALERFLQD YFDGNLKRYL KSEPIPESND GPVKVVVAEN FDEIVNNENK DVLIEFYAPW CGHCKNLEPK YKELGEKLSK DPNIVIAKMD ATANDVPSPY EVRGFPTIYF SPANKKLNPK KYEGGRELSD FISYLQREAT NPPVIQEEKP KKKKKAQEDL
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 206-505 of human ERp57 (NP_005304.3).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
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Autre désignation
- PDIA3
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Sujet
- This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase, however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates.,PDIA3,ER60,ERp57,ERp60,ERp61,GRP57,GRP58,HEL-S-269,HEL-S-93n,HsT17083,P58,PI-PLC,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,PDIA3
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Poids moléculaire
- 56 kDa
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ID gène
- 2923
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UniProt
- P30101
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Pathways
- Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis
Antigène
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