TTR anticorps (AA 21-147)

N° du produit ABIN3021474

Cet anticorps Lapin Polyclonal détecte spécifiquement TTR dans WB, IHC et IF. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour TTR anticorps (AA 21-147) (ABIN3021474)

Antigène: TTR (Transthyretin (TTR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TTR anticorps

Épitope: AA 21-147

Séquence: GPTGTGESKC PLMVKVLDAV RGSPAINVAV HVFRKAADDT WEPFASGKTS ESGELHGLTT EEEFVEGIYK VEIDTKSYWK ALGISPFHEH AEVVFTANDS GPRRYTIAAL LSPYSYSTTA VVTNPKE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 21-147 of human TTR (NP_000362.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-TTR (ABIN3021474)

Tesch, Abdirama, Grießbach, Brand, Goerlich, Humrich, Bacher, Hiepe, Riemekasten, Enghard: "Identification and characterization of antigen-specific CD4+ T cells targeting renally expressed antigens in human lupus nephritis with two independent methods." dans: Scientific reports, Vol. 10, Issue 1, pp. 21312, (2020) (PubMed).

Détails sur TTR

Antigène: TTR (Transthyretin (TTR))

Autre désignation: TTR

Sujet: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.,TTR,CTS,CTS1,HEL111,HsT2651,PALB,TBPA,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,Blood,Serum Proteins,TTR

Poids moléculaire: 15 kDa

ID gène: 7276

UniProt: P02766

Pathways: Hormone Transport