Tropomyosin anticorps (AA 1-245)

N° du produit ABIN3021578

Cet anticorps anti-Tropomyosin est un anticorps Lapin Polyclonal détectant Tropomyosin dans WB, IHC et IF. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour Tropomyosin anticorps (AA 1-245) (ABIN3021578)

Antigène: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tropomyosin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Tropomyosin anticorps

Épitope: AA 1-245

Séquence: MAGSSSLEAV RRKIRSLQEQ ADAAEERAGT LQRELDHERK LRETAEADVA SLNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIESRAQK DEEKMEIQEI QLKEAKHIAE DADRKYEEVA RKLVIIESDL ERAEERAELS EGKCAELEEE LKTVTNNLKS LEAQAEKYSQ KEDRYEEEIK VLSDKLKEAE TRAEFAERSV TKLEKSIDDL EDQLYQQLEQ NRRLTNELKL ALNED

Réactivité croisée: Humain, Souris, Rat, Poisson zèbre (Danio rerio)

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human Tropomyosin 1 (NP_001018008.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Tropomyosin (ABIN3021578)

Wu, Lou, Ge, Xiong: "Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos." dans: Scientific reports, Vol. 7, Issue 1, pp. 4022, (2018) (PubMed).

Détails sur Tropomyosin

Antigène: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Autre désignation: TPM1

Sujet: This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.,TPM1,C15orf13,CMD1Y,CMH3,HEL-S-265,HTM-alpha,LVNC9,TMSA,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,Cardiovascular,Heart,Hypertrophy,TPM1

Poids moléculaire: 26 kDa/28 kDa/32 kDa

ID gène: 7168

UniProt: P09493

Pathways: Regulation of Actin Filament Polymerization