UGDH anticorps (AA 165-494)
Aperçu rapide pour UGDH anticorps (AA 165-494) (ABIN3021733)
Antigène
Voir toutes UGDH AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 165-494
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Séquence
- EGTAIKDLKN PDRVLIGGDE TPEGQRAVQA LCAVYEHWVP REKILTTNTW SSELSKLAAN AFLAQRISSI NSISALCEAT GADVEEVATA IGMDQRIGNK FLKASVGFGG SCFQKDVLNL VYLCEALNLP EVARYWQQVI DMNDYQRRRF ASRIIDSLFN TVTDKKIAIL GFAFKKDTGD TRESSSIYIS KYLMDEGAHL HIYDPKVPRE QIVVDLSHPG VSEDDQVSRL VTISKDPYEA CDGAHAVVIC TEWDMFKELD YERIHKKMLK PAFIFDGRRV LDGLHNELQT IGFQIETIGK KVSSKRIPYA PSGEIPKFSL QDPPNKKPKV
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 165-494 of human UGDH (NP_003350.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))
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Autre désignation
- UGDH
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Sujet
- The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.,UGDH,GDH,UDP-GlcDH,UDPGDH,UGD,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Amino acid metabolism,UGDH
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Poids moléculaire
- 44 kDa/47 kDa/55 kDa
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ID gène
- 7358
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UniProt
- O60701
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Pathways
- Glycosaminoglycan Metabolic Process
Antigène
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