Fibrinogen beta Chain anticorps (AA 202-491)
Aperçu rapide pour Fibrinogen beta Chain anticorps (AA 202-491) (ABIN3021950)
Antigène
Voir toutes Fibrinogen beta Chain (FGB) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 202-491
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Séquence
- LENLRSKIQK LESDVSAQME YCRTPCTVSC NIPVVSGKEC EEIIRKGGET SEMYLIQPDS SVKPYRVYCD MNTENGGWTV IQNRQDGSVD FGRKWDPYKQ GFGNVATNTD GKNYCGLPGE YWLGNDKISQ LTRMGPTELL IEMEDWKGDK VKAHYGGFTV QNEANKYQIS VNKYRGTAGN ALMDGASQLM GENRTMTIHN GMFFSTYDRD NDGWLTSDPR KQCSKEDGGG WWYNRCHAAN PNGRYYWGGQ YTWDMAKHGT DDGVVWMNWK GSWYSMRKMS MKIRPFFPQQ
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 202-491 of human FGB (NP_005132.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Fibrinogen beta Chain (FGB)
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Autre désignation
- FGB
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Sujet
- The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,FGB,HEL-S-78p,Cardiovascular,Blood,Coagulation,FGB
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Poids moléculaire
- 55 kDa
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ID gène
- 2244
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UniProt
- P02675
Antigène
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