Glucose-6-Phosphate Dehydrogenase anticorps (AA 246-545)

N° du produit ABIN3022095

Cité dans 2 publications. Cet anticorps anti-Glucose-6-Phosphate Dehydrogenase Polyclonal Lapin (ABIN3022095) détecte spécifiquement Glucose-6-Phosphate Dehydrogenase dans WB et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Glucose-6-Phosphate Dehydrogenase anticorps (AA 246-545) (ABIN3022095)

Antigène: Glucose-6-Phosphate Dehydrogenase (G6PD)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glucose-6-Phosphate Dehydrogenase est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Glucose-6-Phosphate Dehydrogenase anticorps

Épitope: AA 246-545

Séquence: FANRIFGPIW NRDNIACVIL TFKEPFGTEG RGGYFDEFGI IRDVMQNHLL QMLCLVAMEK PASTNSDDVR DEKVKVLKCI SEVQANNVVL GQYVGNPDGE GEATKGYLDD PTVPRGSTTA TFAAVVLYVE NERWDGVPFI LRCGKALNER KAEVRLQFHD VAGDIFHQQC KRNELVIRVQ PNEAVYTKMM TKKPGMFFNP EESELDLTYG NRYKNVKLPD AYERLILDVF CGSQMHFVRS DELREAWRIF TPLLHQIELE KPKPIPYIYG SRGPTEADEL MKRVGFQYEG TYKWVNPHKL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 246-545 of human G6PD (NP_000393.4).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Glucose-6-Phosphate Dehydrogenase (ABIN3022095)

Yang, He, Yao, Tan, Zhu, Li, Guo, Wei: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." dans: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).

Wang, Liang, Lian, Liu, Zhao, Xuan, Guo, Liu, Yang, Dong, Liu, Liu, Zhang: "Identification of proteins responsible for adriamycin resistance in breast cancer cells using proteomics analysis." dans: Scientific reports, Vol. 5, pp. 9301, (2016) (PubMed).

Détails sur Glucose-6-Phosphate Dehydrogenase

Antigène: Glucose-6-Phosphate Dehydrogenase (G6PD)

Autre désignation: G6PD

Sujet: This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.,G6PD,G6PD1,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Endocrine and metabolic diseases,Diabetes,Cardiovascular,Heart,Cardiac metabolism,Cardiovascular diseases,Heart disease,G6PD

Poids moléculaire: 59 kDa/62 kDa/63 kDa

ID gène: 2539

UniProt: P11413

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones