Muscarinic Acetylcholine Receptor M2 anticorps (AA 208-388)
Aperçu rapide pour Muscarinic Acetylcholine Receptor M2 anticorps (AA 208-388) (ABIN3022149)
Antigène
Voir toutes Muscarinic Acetylcholine Receptor M2 (CHRM2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 208-388
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Séquence
- HISRASKSRI KKDKKEPVAN QDPVSPSLVQ GRIVKPNNNN MPSSDDGLEH NKIQNGKAPR DPVTENCVQG EEKESSNDST SVSAVASNMR DDEITQDENT VSTSLGHSKD ENSKQTCIRI GTKTPKSDSC TPTNTTVEVV GSSGQNGDEK QNIVARKIVK MTKQPAKKKP PPSREKKVTR T
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Réactivité croisée
- Humain
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 208-388 of human Muscarinic AChR M2 (ACM2) (NP_001006629.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
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Autre désignation
- CHRM2
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Sujet
- The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.,CHRM2,HM2,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRM2
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Poids moléculaire
- 51 kDa
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ID gène
- 1129
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UniProt
- P08172
Antigène
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