anticorps AT3, anticorps AT3D, anticorps ATIII, anticorps THPH7, anticorps SERPINC1, anticorps DKFZp470C1733, anticorps AI114908, anticorps At-3, anticorps At3, anticorps ANTITHROMBIN, AT-III, anticorps AT-III, anticorps serpin family C member 1, anticorps antithrombin-III, anticorps serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1, anticorps SERPINC1, anticorps CpipJ_CPIJ000472, anticorps CpipJ_CPIJ013111, anticorps Serpinc1
Sujet
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.,SERPINC1,AT3,AT3D,ATIII,THPH7,Stem Cells,Cardiovascular,Blood,Coagulation,Serum Proteins,SERPINC1