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Renin anticorps (AA 24-160)

REN Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3022188
  • Antigène Voir toutes Renin (REN) Anticorps
    Renin (REN)
    Épitope
    • 15
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-160
    Reactivité
    • 54
    • 44
    • 33
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 65
    • 19
    • 16
    • 2
    • 2
    Lapin
    Clonalité
    • 84
    • 19
    Polyclonal
    Conjugué
    • 46
    • 17
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Renin est non-conjugé
    Application
    • 78
    • 47
    • 36
    • 13
    • 13
    • 12
    • 11
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    LPTDTTTFKR IFLKRMPSIR ESLKERGVDM ARLGPEWSQP MKRLTLGNTT SSVILTNYMD TQYYGEIGIG TPPQTFKVVF DTGSSNVWVP SSKCSRLYTA CVYHKLFDAS DSSSYKHNGT ELTLRYSTGT VSGFLSQ
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 24-160 of human Renin (NP_000528.1).
    Isotype
    IgG
    Top Product
    Discover our top product REN Anticorps primaire
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:100 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze / thaw cycles
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    Renin (REN)
    Autre désignation
    REN (REN Produits)
    Synonymes
    anticorps HNFJ2, anticorps RATRENAA, anticorps RENAA, anticorps Ren1, anticorps D19352, anticorps Ren, anticorps Ren-1, anticorps Ren-A, anticorps Ren1c, anticorps Ren1d, anticorps Rn-1, anticorps Rnr, anticorps renin, anticorps renin 1 structural, anticorps REN, anticorps Ren, anticorps Ren1, anticorps ren
    Sujet
    Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.,REN,HNFJ2,renin,Renin,Cardiovascular,Blood,Blood Pressure regulation,REN
    Poids moléculaire
    44 kDa/45 kDa
    ID gène
    5972
    UniProt
    P00797
    Pathways
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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