DPYD anticorps (AA 1-173)

N° du produit ABIN3022259

Cet anticorps Lapin Polyclonal détecte spécifiquement DPYD dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour DPYD anticorps (AA 1-173) (ABIN3022259)

Antigène: DPYD (Dihydropyrimidine Dehydrogenase (DPYD))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPYD est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DPYD anticorps

Épitope: AA 1-173

Séquence: MAPVLSKDSA DIESILALNP RTQTHATLCS TSAKKLDKKH WKRNPDKNCF NCEKLENNFD DIKHTTLGER GALREAMRCL KCADAPCQKS CPTNLDIKSF ITSIANKNYY GAAKMIFSDN PLGLTCGMVC PTSDLCVGGC NLYATEEGPI NIGGLQQFAT ETLILAFSLM NHL

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human DPYD (NP_001153773.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DPYD

Antigène: DPYD (Dihydropyrimidine Dehydrogenase (DPYD))

Autre désignation: DPYD

Sujet: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.,DPYD,DHP,DHPDHASE,DPD,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,DPYD

Poids moléculaire: 18 kDa/111 kDa

ID gène: 1806

UniProt: Q12882

Pathways: Ribonucleoside Biosynthetic Process