KNG1 anticorps (AA 148-427)
Aperçu rapide pour KNG1 anticorps (AA 148-427) (ABIN3022364)
Antigène
Voir toutes KNG1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 148-427
-
Séquence
- PISTQSPDLE PILRHGIQYF NNNTQHSSLF MLNEVKRAQR QVVAGLNFRI TYSIVQTNCS KENFLFLTPD CKSLWNGDTG ECTDNAYIDI QLRIASFSQN CDIYPGKDFV QPPTKICVGC PRDIPTNSPE LEETLTHTIT KLNAENNATF YFKIDNVKKA RVQVVAGKKY FIDFVARETT CSKESNEELT ESCETKKLGQ SLDCNAEVYV VPWEKKIYPT VNCQPLGMIS LMKRPPGFSP FRSSRIGEIK EETTSHLRSC EYKGRPPKAG AEPASEREVS
-
Réactivité croisée
- Humain, Souris, Rat
-
Attributs du produit
- Polyclonal Antibodies
-
Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 148-427 of human Kininogen 1 (Kininogen 1 (KNG1)) (NP_000884.1).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid freeze / thaw cycles
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- KNG1 (Kininogen 1 (KNG1))
-
Autre désignation
- KNG1
-
Sujet
- This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.,KNG1,BDK,BK,KNG,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Apoptosis,Cardiovascular,Blood,KNG1
-
Poids moléculaire
- 43 kDa/47 kDa/71 kDa
-
ID gène
- 3827
-
UniProt
- P01042
-
Pathways
- ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
Antigène
-