Claudin 7 anticorps (AA 29-211)
Aperçu rapide pour Claudin 7 anticorps (AA 29-211) (ABIN3022751)
Antigène
Voir toutes Claudin 7 (CLDN7) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 29-211
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Séquence
- QWQMSSYAGD NIITAQAMYK GLWMDCVTQS TGMMSCKMYD SVLALSAALQ ATRALMVVSL VLGFLAMFVA TMGMKCTRCG GDDKVKKARI AMGGGIIFIV AGLAALVACS WYGHQIVTDF YNPLIPTNIK YEFGPAIFIG WAGSALVILG GALLSCSCPG NESKAGYRVP RSYPKSNSSK EYV
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 29-211 of human CLDN7 (NP_001298.3).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Claudin 7 (CLDN7)
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Autre désignation
- CLDN7
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Sujet
- This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.,CLDN7,CEPTRL2,CLDN-7,CPETRL2,Hs.84359,claudin-1,claudin-7,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,CLDN7
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Poids moléculaire
- 16 kDa/22 kDa
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ID gène
- 1366
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UniProt
- O95471
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Pathways
- Hepatitis C
Antigène
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