SORD anticorps (AA 1-357)

N° du produit ABIN3022962

Détail du produit anti-SORD anticorps

Antigène: SORD (Sorbitol Dehydrogenase (SORD))

Épitope: AA 1-357

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SORD est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MAAAAKPNNL SLVVHGPGDL RLENYPIPEP GPNEVLLRMH SVGICGSDVH YWEYGRIGNF IVKKPMVLGH EASGTVEKVG SSVKHLKPGD RVAIEPGAPR ENDEFCKMGR YNLSPSIFFC ATPPDDGNLC RFYKHNAAFC YKLPDNVTFE EGALIEPLSV GIHACRRGGV TLGHKVLVCG AGPIGMVTLL VAKAMGAAQV VVTDLSATRL SKAKEIGADL VLQISKESPQ EIARKVEGQL GCKPEVTIEC TGAEASIQAG IYATRSGGNL VLVGLGSEMT TVPLLHAAIR EVDIKGVFRY CNTWPVAISM LASKSVNVKP LVTHRFPLEK ALEAFETFKK GLGLKIMLKC DPSDQNP

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-357 of human SORD (NP_003095.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SORD

Antigène: SORD (Sorbitol Dehydrogenase (SORD))

Autre désignation: SORD (SORD Produits)

Synonymes: anticorps SORD1, anticorps Sdh-1, anticorps Sdh1, anticorps Sodh-1, anticorps SDH, anticorps sord, anticorps MGC83437, anticorps BmSDH, anticorps PSPTO0363, anticorps SODH-1, anticorps RATSDHE1, anticorps SDH2, anticorps Sdh, anticorps Sdhe1, anticorps TDH, anticorps 4733401P19Rik, anticorps AI836084, anticorps CGI-97, anticorps SDS, anticorps zgc:63674, anticorps sorbitol dehydrogenase, anticorps sorbitol dehydrogenase L homeolog, anticorps Sorbitol dehydrogenase, anticorps serine dehydratase, anticorps SBDS ribosome maturation factor, anticorps SORD, anticorps Sord, anticorps sord.L, anticorps sord, anticorps Sdh, anticorps LOC733025, anticorps polS, anticorps RS_RS10765, anticorps sdh, anticorps smoS, anticorps Rsph17029_1731, anticorps Srd, anticorps RSKD131_1411, anticorps SDS, anticorps Sds, anticorps Sbds

Sujet: Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.,SORD,HEL-S-95n,SORD1,Cancer,Signal Transduction,Endocrine & Metabolism,SORD

Poids moléculaire: 10 kDa/38 kDa

ID gène: 6652

UniProt: Q00796