ZYX anticorps (AA 1-300)

N° du produit ABIN3023009

Détail du produit anti-ZYX anticorps

Antigène: ZYX (Zyxin (ZYX))

Épitope: AA 1-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZYX est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MAAPRPSPAI SVSVSAPAFY APQKKFGPVV APKPKVNPFR PGDSEPPPAP GAQRAQMGRV GEIPPPPPED FPLPPPPLAG DGDDAEGALG GAFPPPPPPI EESFPPAPLE EEIFPSPPPP PEEEGGPEAP IPPPPQPREK VSSIDLEIDS LSSLLDDMTK NDPFKARVSS GYVPPPVATP FSSKSSTKPA AGGTAPLPPW KSPSSSQPLP QVPAPAQSQT QFHVQPQPQP KPQVQLHVQS QTQPVSLANT QPRGPPASSP APAPKFSPVT PKFTPVASKF SPGAPGGSGS QPNQKLGHPE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human Zyxinin (NP_001010972.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ZYX

Antigène: ZYX (Zyxin (ZYX))

Autre désignation: ZYX (ZYX Produits)

Synonymes: anticorps BcDNA:LD06023, anticorps CG32018, anticorps DLim-1, anticorps DmLIM-1, anticorps Dmel\\CG32018, anticorps Lim102EF, anticorps ZYX102, anticorps Zyx102, anticorps Zyx102EF, anticorps lim, anticorps zyx102, anticorps zyxin, anticorps zgc:171680, anticorps ZYX, anticorps zyx, anticorps MGC145270, anticorps ESP-2, anticorps HED-2, anticorps 9530098H06Rik, anticorps R75157, anticorps Zyxin, anticorps zyxin, anticorps zyxin S homeolog, anticorps zyx-1, anticorps Zyx, anticorps zyx, anticorps ZYX, anticorps EDI_201420, anticorps zyx.S

Sujet: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.,ZYX,ESP-2,HED-2,zyxin,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Microfilaments,Neuroscience,ZYX

Poids moléculaire: 45 kDa/61 kDa

ID gène: 7791

UniProt: Q15942