PLAU anticorps (AA 20-180)

N° du produit ABIN3023142

Cet anticorps Lapin Polyclonal détecte spécifiquement PLAU dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour PLAU anticorps (AA 20-180) (ABIN3023142)

Antigène: PLAU (Plasminogen Activator, Urokinase (PLAU))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAU est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PLAU anticorps

Épitope: AA 20-180

Séquence: GSNELHQVPS NCDCLNGGTC VSNKYFSNIH WCNCPKKFGG QHCEIDKSKT CYEGNGHFYR GKASTDTMGR PCLPWNSATV LQQTYHAHRS DALQLGLGKH NYCRNPDNRR RPWCYVQVGL KPLVQECMVH DCADGKKPSS PPEELKFQCG QKTLRPRFKI I

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 20-180 of human PLAU (NP_002649.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PLAU

Antigène: PLAU (Plasminogen Activator, Urokinase (PLAU))

Autre désignation: PLAU

Sujet: This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,PLAU,ATF,BDPLT5,QPD,UPA,URK,u-PA,urokinase,Cancer,Signal Transduction,Kinase,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,Blood,Hypoxia,PLAU

Poids moléculaire: 46 kDa/48 kDa

ID gène: 5328

UniProt: P00749

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration