ENPP2 anticorps (AA 564-863)
Aperçu rapide pour ENPP2 anticorps (AA 564-863) (ABIN3023334)
Antigène
Voir toutes ENPP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 564-863
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Séquence
- DLGCTCDDKV EPKNKLDELN KRLHTKGSTE ERHLLYGRPA VLYRTRYDIL YHTDFESGYS EIFLMPLWTS YTVSKQAEVS SVPDHLTSCV RPDVRVSPSF SQNCLAYKND KQMSYGFLFP PYLSSSPEAK YDAFLVTNMV PMYPAFKRVW NYFQRVLVKK YASERNGVNV ISGPIFDYDY DGLHDTEDKI KQYVEGSSIP VPTHYYSIIT SCLDFTQPAD KCDGPLSVSS FILPHRPDNE ESCNSSEDES KWVEELMKMH TARVRDIEHL TSLDFFRKTS RSYPEILTLK TYLHTYESEI
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 564-863 of human ENPP2 (NP_001035181.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))
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Autre désignation
- ENPP2
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Sujet
- The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.,ENPP2,ATX,ATX-X,AUTOTAXIN,LysoPLD,NPP2,PD-IALPHA,PDNP2,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Lipases,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Angiogenesis,Heart,Lipids,Cardiovascular diseases,Heart disease,ENPP2
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Poids moléculaire
- 98 kDa/101 kDa/105 kDa
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ID gène
- 5168
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UniProt
- Q13822
Antigène
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