Histone H2A anticorps (pSer139)

N° du produit ABIN3023622

L’anticorps Lapin Polyclonal anti-Histone H2A a été validé pour WB. Il convient pour détecter Histone H2A dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour Histone H2A anticorps (pSer139) (ABIN3023622)

Antigène: Histone H2A

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone H2A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Histone H2A anticorps

Épitope: pSer139

Séquence: TQASQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A synthetic phosphorylated peptide around S139 of human Histone H2AX (NP_002096.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1mg/ml

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-Histone H2A (ABIN3023622)

Xiang, Laurent, Hsu, Nachtergaele, Lu, Sheng, Xu, Chen, Ouyang, Wang, Ling, Hsu, Zou, Jambhekar, He, Shi: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." dans: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).

Détails sur Histone H2A

Antigène: Histone H2A

Sujet: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.,H2A.X,H2A/X,H2AX,Histone H2AX,H2AFX,histone H2AX,gamma H2A.X,γH2AX,Epigenetics & Nuclear Signaling,Histones,DNA Damage & Repair,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Phosphorylation,Histone H2A

Poids moléculaire: 15 kDa

ID gène: 3014

UniProt: P16104