TNFSF15 anticorps
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- Antigène Voir toutes TNFSF15 Anticorps
- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TNFSF15 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Protein G affinity chromatography
- Immunogène
- A human partial recombinant protein was used as the immunogen for this TL1A antibody.
- Clone
- TLRM1-1
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product TNFSF15 Anticorps primaire
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- Indications d'application
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The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the TL1A antibody to be titered up or down for optimal performance.
1. Staining of FFPE tissue requires boiling sections in 10 mM Tris with 1 mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 min.\. FACS: 0.5-1 μg/10^6 cells,IF: 1-2 μg/mL,Western blot: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL (1)
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- Agent conservateur
- Azide free
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store the TL1A antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Antigène
- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
- Autre désignation
- TL1A (TNFSF15 Produits)
- Synonymes
- anticorps TTPAL, anticorps TL1, anticorps TL1A, anticorps VEGI, anticorps VEGI192A, anticorps Tl1, anticorps Tl1a, anticorps Vegi, anticorps tumor necrosis factor superfamily member 15, anticorps TNF superfamily member 15, anticorps tumor necrosis factor (ligand) superfamily, member 15, anticorps TNFSF15, anticorps Tnfsf15
- Sujet
- TNF ligand-related molecule 1 is an anti-angiogenic cytokine that is also called Tumor necrosis factor superfamily, member 15 (TNFSF15) and Vascular endothelial growth inhibitor (VEGI/VEGI192A). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of TL1A has been reported as a marker of poor prognosis in breast cancer.
- ID gène
- 9966
- Pathways
- Positive Regulation of Endopeptidase Activity, Autophagy
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