UACA anticorps

N° du produit ABIN3024023

Cet anticorps Souris Monoclonal détecte spécifiquement UACA dans WB, IF et FACS. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour UACA anticorps (ABIN3024023)

Antigène: UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp UACA est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: AE-5

Détail du produit anti-UACA anticorps

Purification: Protein G affinity chromatography

Immunogène: Nuclei of myeloid leukemia biopsy cells were used as the immunogen for the UACA antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal dilution of the UACA antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the UACA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur UACA

Antigène: UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))

Autre désignation: UACA

Sujet: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

Pathways: Positive Regulation of Endopeptidase Activity