VLDLR anticorps (C-Term)

N° du produit ABIN3024046

Cet anticorps anti-VLDLR est un anticorps Souris Monoclonal détectant VLDLR dans WB, FACS, IF et IHC (p). Adapté pour Humain et Rat.

Aperçu rapide pour VLDLR anticorps (C-Term) (ABIN3024046)

Antigène: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VLDLR est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: VLPR-1

Détail du produit anti-VLDLR anticorps

Épitope: C-Term

Purification: Protein G affinity chromatography

Immunogène: A human partial recombinant protein from the C-terminal region was used as the immunogen for this VLDLR antibody.

Isotype: IgG1

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the VLDLR antibody to be titered up or down for optimal performance.

1. Staining of FFPE tissue is enhanced by boiling sections in 10  mM Tris with 1  mM EDTA,  pH 9 for 10-20 min followed by cooling at RT for 20 min.\. FACS: 0.5-1 μg/10^6 cells,IF: 1-2 μg/mL,Western blot: 1-2 μg/mL,IHC (FFPE): 1-2 μg/mL (1)

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the VLDLR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur VLDLR

Antigène: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Autre désignation: VLDLR

Sujet: Very Low Density Lipoprotein Receptor (VLDLR/VLDL receptor) is a member of the LDL receptor gene family which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDL receptor is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

ID gène: 7436

Pathways: Cellular Response to Molecule of Bacterial Origin