VLDLR anticorps (C-Term)

N° du produit ABIN3024046

Détail du produit anti-VLDLR anticorps

Antigène: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Épitope: C-Term

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VLDLR est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Protein G affinity chromatography

Immunogène: A human partial recombinant protein from the C-terminal region was used as the immunogen for this VLDLR antibody.

Clone: VLPR-1

Isotype: IgG1

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the VLDLR antibody to be titered up or down for optimal performance.

1. Staining of FFPE tissue is enhanced by boiling sections in 10  mM Tris with 1  mM EDTA,  pH 9 for 10-20 min followed by cooling at RT for 20 min.\. FACS: 0.5-1 μg/10^6 cells,IF: 1-2 μg/mL,Western blot: 1-2 μg/mL,IHC (FFPE): 1-2 μg/mL (1)

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the VLDLR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur VLDLR

Antigène: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Autre désignation: VLDLR (VLDLR Produits)

Synonymes: anticorps CARMQ1, anticorps CHRMQ1, anticorps VLDLRCH, anticorps AA408956, anticorps AI451093, anticorps AW047288, anticorps vldlr, anticorps very low density lipoprotein receptor, anticorps very low density lipoprotein receptor S homeolog, anticorps VLDLR, anticorps Vldlr, anticorps vldlr.S

Sujet: Very Low Density Lipoprotein Receptor (VLDLR/VLDL receptor) is a member of the LDL receptor gene family which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDL receptor is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

ID gène: 7436

Pathways: Cellular Response to Molecule of Bacterial Origin